SCHEMBL18212405

SCHEMBL18212405

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccc6oc7ccccc7c6c5)n4)c3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 4/20 0.49
▸ PLA2G4A P47712 4/20 0.49
▸ PLA2G10 O15496 1/20 0.49
▸ HPGD P15428 5/20 0.47
▸ MAPT P10636 5/20 0.47
▸ MEN1 O00255 5/20 0.47
▸ KMT2A Q03164 5/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ NPC1 O15118 4/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ KDM4E B2RXH2 2/20 0.47
▸ CHEK2 O96017 1/20 0.44
▸ AHR P35869 1/20 0.43
▸ LMNA P02545 2/20 0.41
▸ ATM Q13315 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ GABRP O00591 1/20 0.40
▸ GABRD O14764 1/20 0.40
▸ CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23268363 1.00 PLA2G2A (0.49) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL21023694 0.98 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL21784914 0.98 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL23268163 0.98 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL25458938 0.98 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL15501281 0.98 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL18561907 0.98 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL21109060 0.97 PLA2G2A (0.50) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL21108989 0.97 PLA2G2A (0.50) PLA2G2APLA2G4APLA2G10HPGDMAPT
SCHEMBL21109063 0.97 PLA2G2A (0.50) PLA2G2APLA2G4APLA2G10HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 — — US disclosed
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 — — US disclosed
US-10403826-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 — — US disclosed
US-20160329502-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-11-10 — — US disclosed
US-20160329502-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403826-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND PLA2G2A 3705/4885PLA2G4A 4367/4885PLA2G10 4521/4885
US-11744151-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND PLA2G2A 3705/4885PLA2G4A 4367/4885PLA2G10 4521/4885
US-20160329502-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND PLA2G2A 3705/4885PLA2G4A 4367/4885PLA2G10 4521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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