SCHEMBL18212422

SCHEMBL18212422

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccc6sc7ccccc7c6c5)n4)c3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.45
CYP1A2 P05177 2/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
PIM3 Q86V86 1/20 0.40
ATM Q13315 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
GLA P06280 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTPN7 P35236 1/20 0.38
DUSP3 P51452 1/20 0.38
PTPN12 Q05209 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22058664 0.98 GPR3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL15501448 0.98 GPR3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL25000309 0.98 GPR3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL15501452 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL21108991 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL15501663 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL15501664 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL25645645 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL25645646 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT
SCHEMBL25645685 0.97 PIM3 (0.44) GPR3CYP1A2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-10403826-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
US-20160329502-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-11-10 US disclosed
US-20160329502-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403826-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND GPR3 1285/4885CYP1A2 366/4885MEN1 4702/4885
US-11744151-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND GPR3 1285/4885CYP1A2 366/4885MEN1 4702/4885
US-20160329502-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND GPR3 1285/4885CYP1A2 366/4885MEN1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.