Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663680 | 0.72 | NOTUM (0.41) | MAPTKMT2AKDM4ESMN1; SMN2POLB | |
| SCHEMBL13555544 | 0.72 | KDM4E (0.38) | CYP2C9KDM4EHSD17B10HTT | |
| SCHEMBL27353963 | 0.72 | BRD4 (0.31) | BRD4CYP2C9KDM4E | |
| SCHEMBL10526527 | 0.70 | MAOB (0.36) | L3MBTL1MAOBKMT2AKDM4EHSD17B10 | |
| SCHEMBL13774352 | 0.68 | KDM4E (0.51) | BRD4L3MBTL1MAOBMAPTKMT2A | |
| SCHEMBL17341802 | 0.68 | BRD4 (0.38) | BRD4L3MBTL1HDAC8SMN1; SMN2 | |
| SCHEMBL22641328 | 0.68 | HSP90AB1 (0.36) | BRD4L3MBTL1MAPTKMT2AKDM4E | |
| SCHEMBL4510662 | 0.67 | LMNA (0.65) | BRD4L3MBTL1MAOBMAPTKMT2A | |
| SCHEMBL12249887 | 0.67 | GMNN (0.30) | BRD4MAPTLMNA | |
| SCHEMBL12249886 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326165-A1 | ALKOXYCARBONYL HEMIACETAL-TYPE ESTER PRODRUG OF PYRIDONE CARBOXYLIC ACID ANTIBACTERIAL DRUG | KINKI UNIVERSITY (JP) | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326165-A1 | ALKOXYCARBONYL HEMIACETAL-TYPE ESTER PRODRUG OF PYRIDONE CARBOXYLIC ACID ANTIBACTERIAL DRUG | ALPI, CYP2B6, CYP2A6 | BRD4 4664/4885L3MBTL1 1739/4885MAOB 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.