Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666618 | 0.93 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL7901749 | 0.88 | — | — | |
| SCHEMBL16203243 | 0.83 | MEN1 (0.34) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL23694376 | 0.83 | ALDH1A1 (0.41) | TSHRTHRBALDH1A1TP53HIF1A | |
| SCHEMBL16259310 | 0.83 | CA1 (0.39) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL13880149 | 0.83 | ALDH1A1 (0.30) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13618820 | 0.83 | HSD17B10 (0.40) | MEN1KMT2ATSHRTHRBHTT | |
| SCHEMBL724449 | 0.82 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL12231853 | 0.80 | ALDH1A1 (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL1104284 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016177677-A1 | SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2016-11-10 | — | — | WO | disclosed |