⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149732 | 0.91 | — | — | |
| SCHEMBL10148662 | 0.85 | — | — | |
| SCHEMBL18697933 | 0.82 | — | — | |
| SCHEMBL18214612 | 0.78 | — | — | |
| SCHEMBL881388 | 0.78 | — | — | |
| SCHEMBL12397153 | 0.78 | — | — | |
| SCHEMBL18214657 | 0.77 | POLRMT (0.38) | — | |
| SCHEMBL10149731 | 0.76 | — | — | |
| SCHEMBL12393317 | 0.75 | — | — | |
| SCHEMBL12761526 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480552-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2016-11-09 | — | — | EP | disclosed |