Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PRKCG | P05129 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 2/20 | 0.43 |
| ▸ | NEK4 | P51957 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.43 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548293 | 1.00 | CASR (0.45) | CASRROCK1MAP4K4PRKCGCDK1 | |
| Hydrochloric Acid SCHEMBL17939846 | 0.99 | CASR (0.45) | CASRROCK1MAP4K4PRKCGCDK1 | |
| SCHEMBL18215359 | 0.89 | CASR (0.47) | CASRMAPK1PFKFB3L3MBTL1NR3C1 | |
| SCHEMBL16548308 | 0.89 | CASR (0.47) | CASRMAPK1PFKFB3L3MBTL1NR3C1 | |
| Hydrochloric Acid SCHEMBL17939920 | 0.88 | CASR (0.46) | CASRMAPK1PFKFB3L3MBTL1NR3C1 | |
| SCHEMBL16548307 | 0.87 | MEN1 (0.47) | CASRROCK1MAP4K4PRKCGCDK1 | |
| Hydrochloric Acid SCHEMBL17939978 | 0.86 | MEN1 (0.46) | CASRROCK1MAP4K4PRKCGCDK1 | |
| SCHEMBL18584823 | 0.86 | CYP11B1 (0.46) | CASRROCK1MAP4K4PRKCGCDK1 | |
| SCHEMBL16548154 | 0.85 | ROCK1 (0.48) | CASRROCK1MAP4K4PRKCGCDK1 | |
| Hydrochloric Acid SCHEMBL16540150 | 0.85 | ROCK1 (0.47) | CASRROCK1MAP4K4PRKCGCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |