SCHEMBL18215380

SCHEMBL18215380

CCC(CCCS(=O)(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.61
MAPK1 P28482 1/20 0.61
GCLC P48506 2/20 0.47
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 4/20 0.39
SLC1A2 P43004 3/20 0.39
SLC1A1 P43005 3/20 0.39
SLC1A3 P43003 2/20 0.39
GRIK1 P39086 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethylhexanoic Acid SCHEMBL28124121 0.82 CA2 (0.83) CA2MAPK1GCLCCHRM1AKR1A1
SCHEMBL14360108 0.80 CA2 (0.81) CA2MAPK1GCLCCHRM1AKR1A1
SCHEMBL10897254 0.80 CA2 (0.81) CA2MAPK1GCLCCHRM1AKR1A1
SCHEMBL11189150 0.79 CA2 (0.65) CA2MAPK1GCLCCA1APP
2-Ethylhexanoic Acid SCHEMBL28194386 0.79 CA2 (0.95) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL27901184 0.78 CA2 (0.77) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL14359878 0.78 CA2 (0.77) CA2MAPK1CHRM1AKR1A1CHRM3
Ammonia Solution, Strong SCHEMBL28267146 0.78 CA2 (0.77) CA2MAPK1GCLCCHRM1AKR1A1
SCHEMBL14360381 0.78 CA2 (0.77) CA2MAPK1CHRM1AKR1A1CHRM3
2-Ethylhexanoic Acid SCHEMBL8375903 0.76 CA2 (1.00) CA2MAPK1CHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9493582-B2 Alkylated cyclodextrin compositions and processes for preparing and using the same CYDEX PHARMACEUTICALS, INC. (US) 2016-11-15 US disclosed