Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356580 | 1.00 | POLB (0.38) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL13052708 | 0.96 | TDP1 (0.41) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14790873 | 0.91 | ELANE (0.34) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17061428 | 0.91 | TDP1 (0.44) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL25755577 | 0.88 | TDP1 (0.41) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14181196 | 0.86 | TDP1 (0.41) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL2368083 | 0.84 | TDP1 (0.41) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL9764044 | 0.82 | TDP1 (0.45) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL2367678 | 0.81 | TDP1 (0.44) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17061426 | 0.81 | TDP1 (0.44) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010406-B2 | Using the light adjustable lens (LAL) to increase the depth of focus by inducing targeted amounts of asphericity | RXSIGHT, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20160324629-A1 | USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY | CALHOUN VISION, INC. (US) | 2016-11-10 | — | — | US | disclosed |