SCHEMBL25755577

SCHEMBL25755577

C=C(C)C(=O)OCCC[Si](C)(C)O[Si](C)(O[Si](C)(C)C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.33
ELANE P08246 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17061428 0.96 TDP1 (0.44) TDP1POLBAPEX1HTTTSHR
SCHEMBL13052708 0.92 TDP1 (0.41) TDP1POLBAPEX1HTTTSHR
SCHEMBL14181196 0.92 TDP1 (0.41) TDP1POLBAPEX1HTTTSHR
SCHEMBL9763744 0.88 TDP1 (0.41) TDP1POLBAPEX1HTTTSHR
SCHEMBL15356580 0.88 POLB (0.38) TDP1POLBAPEX1HTTTSHR
SCHEMBL18216802 0.88 POLB (0.38) TDP1POLBAPEX1HTTTSHR
SCHEMBL9764044 0.87 TDP1 (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL17061426 0.86 TDP1 (0.44) TDP1POLBAPEX1HTTTSHR
SCHEMBL2367678 0.86 TDP1 (0.44) TDP1POLBAPEX1HTTTSHR
SCHEMBL1398279 0.86 TDP1 (0.44) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203225-A1 COMPOSITION FOR ENCAPSULATING ORGANIC LIGHT EMITTING ELEMENT AND ORGANIC LIGHT EMITTING ELEMENT DISPLAY DEVICE MANUFACTURED THEREFROM SAMSUNG SDI CO LTD (KR) 2023-06-29 US disclosed
US-20230203225-A1 COMPOSITION FOR ENCAPSULATING ORGANIC LIGHT EMITTING ELEMENT AND ORGANIC LIGHT EMITTING ELEMENT DISPLAY DEVICE MANUFACTURED THEREFROM SAMSUNG SDI CO LTD (KR) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203225-A1 COMPOSITION FOR ENCAPSULATING ORGANIC LIGHT EMITTING ELEMENT AND ORGANIC LIGHT EMITTING ELEMENT DISPLAY DEVICE MANUFACTURED THEREFROM ORMDL3, NOTUM, WEE1 TDP1 2787/4885POLB 3654/4885APEX1 3137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.