SCHEMBL18218320

SCHEMBL18218320

O=Cc1cc(CO)cc(CO)c1O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.57
CASP6 P55212 1/20 0.57
ERN1 O75460 8/20 0.43
SHBG P04278 1/20 0.41
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
EGFR P00533 1/20 0.39
ACHE P22303 1/20 0.38
CDK1 P06493 1/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
AOX1 Q06278 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29942736 1.00 KDM4E (0.57) KDM4ECASP6ERN1SHBGMAPT
SCHEMBL18218311 0.89 ERN1 (0.44) KDM4ECASP6ERN1SHBGMAPT
SCHEMBL19411066 0.87 ERN1 (0.54) KDM4ECASP6ERN1MAPTLMNA
SCHEMBL18218317 0.87 KDM4E (0.43) KDM4ECASP6ERN1SHBGMAPT
SCHEMBL18218325 0.85 SHBG (0.52) KDM4ECASP6ERN1SHBGMAPT
SCHEMBL20979755 0.82 ERN1 (0.44) KDM4ECASP6ERN1MAPTLMNA
SCHEMBL19411067 0.80 ERN1 (0.42) KDM4ECASP6ERN1LMNAMEN1
SCHEMBL18218322 0.78 ERN1 (0.60) KDM4ECASP6ERN1
SCHEMBL5021200 0.78 ERN1 (0.67) KDM4ECASP6ERN1ALDH1A1HPGD
SCHEMBL11650048 0.78 ERN1 (0.67) KDM4ECASP6ERN1SHBGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230324802-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING INDOLOCARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-10-12 US disclosed
US-11720024-B2 Resist underlayer film-forming composition containing indolocarbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-08-08 US disclosed
US-11472946-B2 High stiffness rubber composition COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-10-18 US disclosed
US-20210347966-A1 HIGH STIFFNESS RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-11-11 US disclosed
US-11091580-B2 High strength rubber composition COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-08-17 US disclosed
US-20200031980-A1 HIGH STRENGTH RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-01-30 US disclosed
US-20160326396-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING NOVOLAC POLYMER HAVING SECONDARY AMINO GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-11-10 US disclosed