Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759060 | 0.86 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL20049933 | 0.77 | PRMT5 (0.73) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL4333075 | 0.77 | KMT2A (0.61) | HRH3MEN1KMT2AALDH1A1GAA | |
| SCHEMBL4338285 | 0.77 | KMT2A (0.61) | HRH3MEN1KMT2AALDH1A1GAA | |
| SCHEMBL19648494 | 0.76 | MEN1 (0.57) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL28685631 | 0.73 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL28685627 | 0.73 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL28704316 | 0.73 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL3569235 | 0.72 | BCHE (0.83) | HRH3BCHEACHE | |
| SCHEMBL21759103 | 0.72 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896450-B2 | Modulators of Clavibacter michiganensis and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896450-B2 | Modulators of Clavibacter michiganensis and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160326174-A1 | MODULATORS OF CLAVIBACTER MICHIGANENSIS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2016-11-10 | — | — | US | disclosed |
| US-20160326174-A1 | MODULATORS OF CLAVIBACTER MICHIGANENSIS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326174-A1 | MODULATORS OF CLAVIBACTER MICHIGANENSIS AND METHODS OF MAKING AND USING THEREOF | NOTUM, CMPK1, GGPS1 | HRH3 4509/4885MEN1 2749/4885KMT2A 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.