SCHEMBL182213

SCHEMBL182213

COC1=NCCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343290 0.86
SCHEMBL343294 0.79
SCHEMBL12701552 0.76 NOS3 (0.30)
SCHEMBL18989126 0.76
SCHEMBL4475548 0.68 NOS3 (0.36)
SCHEMBL10062393 0.67
SCHEMBL2923416 0.62
SCHEMBL10027875 0.62
SCHEMBL11881679 0.62
SCHEMBL693264 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720040-A1 SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT Lario Therapeutics Limited (GB) 2026-04-08 EP disclosed
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 US disclosed
WO-2025215082-A1 FUSED AZINES FOR THE TREATMENT OF INFLAMMATORY DISEASES GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-10-16 WO disclosed
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2025-07-24 US disclosed
EP-4291552-B1 MODULATORS OF COMPLEX I BOEHRINGER INGELHEIM INT (DE) 2025-04-09 EP disclosed
CN-119119079-A Pyrimidinone compounds, preparation method thereof, pharmaceutical composition and application thereof 上海深势唯思科技有限责任公司 2024-12-13 CN disclosed
WO-2024246522-A1 SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT LARIO THERAPEUTICS LIMITED (GB) 2024-12-05 WO disclosed
US-12071403-B2 Modulators of complex I BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-08-27 US disclosed
EP-4416150-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM Sciences Inc (KR) 2024-08-21 EP disclosed
CN-118159540-A Novel capsid assembly inhibitor 南韩商AM科学股份有限公司 2024-06-07 CN disclosed
US-6344453-B1 Insecticidal heterocyclic compounds SHIOKAWA KOZO (JP) 2002-02-05 US disclosed
US-6232309-B1 2-CHLOROPYRIDINE OR 2-CHLOROTHIAZOLE DERIVATIVES OF HETEROCYCLIC COMPOUNDS USED AS PESTICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-05-15 US disclosed
US-5719146-A AGRICULTURE; FORESTRY; STORAGE; HYGIENE NIHON BAYER AGROCHEM K.K. (JP) 1998-02-17 US disclosed
EP-0386565-B1 Heterocyclic compounds BAYER AGROCHEM KK (JP) 1994-01-12 EP disclosed
US-5034524-A Insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-07-23 US disclosed
US-5032589-A Insecticidal heterocyclic compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-07-16 US disclosed
EP-0386565-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1990-09-12 EP disclosed
US-4315767-A Triazolone herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-16 US disclosed
US-4214891-A Triazolone herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed
US-4139364-A Triazolone herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-02-13 US disclosed