Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 10/20 | 0.53 |
| ▸ | FABP3 | P05413 | 9/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 9/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14917232 | 0.85 | FABP4 (0.70) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18222163 | 0.84 | FABP4 (0.69) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18222149 | 0.83 | FABP4 (0.71) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14917297 | 0.80 | FABP4 (0.53) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14916151 | 0.80 | FABP4 (0.49) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18222212 | 0.80 | NPSR1 (0.70) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18222158 | 0.78 | FABP4 (0.61) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18222170 | 0.78 | FABP4 (0.55) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18222221 | 0.78 | FABP4 (0.62) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14916882 | 0.77 | FABP4 (0.51) | FABP4FABP3FABP5NPSR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773619-B1 | NEW ARYL-QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2016-11-16 | — | — | EP | claimed |