Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 17/20 | 0.63 |
| ▸ | PPARA | Q07869 | 16/20 | 0.63 |
| ▸ | PPARD | Q03181 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543001 | 0.92 | PGR (0.81) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543002 | 0.92 | PGR (0.81) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543632 | 0.92 | PGR (0.81) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL542898 | 0.91 | PGR (0.68) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| Calcium SCHEMBL1336471 | 0.91 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543589 | 0.91 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| Calcium SCHEMBL543457 | 0.91 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL1336464 | 0.91 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL1338479 | 0.88 | PPARG (0.66) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL1827567 | 0.87 | PGR (0.63) | PGRADORA3CHRM1TBXA2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414439-B1 | NOVEL PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINE | CADILA HEALTHCARE LTD (IN) | 2011-05-04 | — | — | EP | disclosed |