SCHEMBL182271

SCHEMBL182271

C1CCC(=NC2CCCCC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
EPHX1 P07099 1/20 0.38
HIF1A Q16665 1/20 0.38
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 2/20 0.35
HSD11B1 P28845 11/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17053448 1.00 TSHR (0.39) TSHRCASP1EPHX1HIF1AALDH1A1
SCHEMBL31332207 0.94 TSHR (0.39) TSHRCASP1EPHX1HIF1AALDH1A1
SCHEMBL1044305 0.92 TSHR (0.41) TSHRCASP1ALDH1A1KMT2A
SCHEMBL21120173 0.92 TSHR (0.35) TSHRCASP1
SCHEMBL1932059 0.84 TSHR (0.36) TSHRCASP1
SCHEMBL12260068 0.80 PDE7A (0.33) EPHX1HIF1AALDH1A1MAPTKMT2A
SCHEMBL991116 0.80 TSHR (0.41) TSHRCASP1ALDH1A1KMT2A
SCHEMBL29203917 0.79 MAPT (0.35) ALDH1A1MAPTHSD11B1
SCHEMBL12405392 0.75 HSD11B1 (0.36) ALDH1A1MAPTHSD11B1
SCHEMBL16620401 0.75 TSHR (0.30) TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019263-A Method for treating N-cyclohexylidene cyclohexylamine impurity in process of preparing cyclohexylamine by aniline hydrogenation 滨州裕能电子材料股份有限公司 2024-11-26 CN claimed
CN-117567297-A Method for refining cyclohexylamine and method for preparing cyclohexylamine 万华化学集团股份有限公司 2024-02-20 CN claimed
CN-114907214-B Preparation method of dicyclohexylamine 万华化学集团股份有限公司 2023-05-26 CN claimed
CN-111153831-B Preparation method of cyclohexanone oxime 湘潭大学 2022-11-01 CN claimed
CN-114907214-A Preparation method of dicyclohexylamine 万华化学集团股份有限公司 2022-08-16 CN claimed
CN-111253281-A Preparation method of cyclohexanone oxime 湘潭大学 2020-06-09 CN claimed
EP-2601170-A1 PROCESS FOR THE PRODUCTION OF HIGHLY PURE DICYCLOHEXYLAMINE FROM BY-PRODUCTS RESULTING FROM THE PRODUCTON OF CYCLOHEXYLAMINE Duslo, A.S. (SK) 2013-06-12 EP claimed
WO-2012018310-A1 PROCESS FOR THE PRODUCTION OF HIGHLY PURE DICYCLOHEXYLAMINE FROM BY-PRODUCTS RESULTING FROM THE PRODUCTON OF CYCLOHEXYLAMINE DUSLO, A.S. (SK) 2012-02-09 WO claimed
CN-100519516-C Process for producing cyclohexanone oxime ASAHI CHEMICAL IND (JP) 2009-07-29 CN claimed
US-7091381-B2 Process for preparation of cyclohexanone oxime ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-08-15 US claimed
CN-1533375-A Process for producing cyclohexanone oxime ɻ�ѧ��ʽ���� 2004-09-29 CN claimed
US-20040176592-A1 Process for preparation of cyclohexanone oxime ASAHI KASEI CHEMICALS CORPORATION (JP) 2004-09-09 US claimed
US-4057581-A CATALYTIC DEHYDROGENATION, NICKEL-CHROMIUM-MANGANESE OR COPPER OR ALUMINUM CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-11-08 US claimed
JP-56057743-A None JP disclosed
CN-119822968-A Preparation method of cyclohexylamine and dicyclohexylamine, and control method of dicyclohexylamine yield in reaction of coproducing dicyclohexylamine from cyclohexylamine 万华化学集团股份有限公司 2025-04-15 CN disclosed
CN-119019263-A Method for treating N-cyclohexylidene cyclohexylamine impurity in process of preparing cyclohexylamine by aniline hydrogenation 滨州裕能电子材料股份有限公司 2024-11-26 CN disclosed
US-4008221-A BACTERICIDE, ANTIBIOTIC RICHARDSON-MERRELL INC. (US) 1977-02-15 US disclosed
US-3994874-A ANTIBACTERIAL RICHARDSON-MERRELL INC. (US) 1976-11-30 US disclosed
US-3956288-A 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives RICHARDSON-MERRELL INC. (US) 1976-05-11 US disclosed
US-3956287-A BACTERICIDES RICHARDSON-MERRELL INC. (US) 1976-05-11 US disclosed