Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230336 | 0.91 | LRRK2 (0.48) | TRPV1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL18230291 | 0.84 | ADORA1 (0.57) | TRPV1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL18230217 | 0.82 | TRPV1 (0.54) | TRPV1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24358156 | 0.82 | MAP3K12 (0.47) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30745724 | 0.82 | MAP3K12 (0.47) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL18230521 | 0.81 | TRPV1 (0.59) | TRPV1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL18230379 | 0.81 | ADORA2A (0.71) | TRPV1MEN1KMT2AMAPTADORA2A | |
| SCHEMBL18230442 | 0.81 | TRPV1 (0.52) | TRPV1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24357968 | 0.81 | MAP3K12 (0.48) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL18230320 | 0.80 | ADORA2A (0.70) | TRPV1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |