Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230443 | 0.91 | TRPV1 (0.48) | TRPV1ADORA2AADORA1SCDTRPV4 | |
| SCHEMBL18230400 | 0.85 | TRPV4 (0.56) | LRRK2TRPV1ADORA2AADORA1TRPV4 | |
| SCHEMBL18230291 | 0.83 | ADORA1 (0.57) | TRPV1ADORA2AADORA1SMN1; SMN2MAPT | |
| SCHEMBL24358171 | 0.82 | GPR52 (0.48) | MAPTMEN1KMT2A | |
| SCHEMBL30745660 | 0.82 | GPR52 (0.48) | MAPTMEN1KMT2A | |
| SCHEMBL18230217 | 0.81 | TRPV1 (0.54) | TRPV1ADORA2AADORA1SMN1; SMN2MAPT | |
| SCHEMBL18230465 | 0.80 | TRPV1 (0.48) | LRRK2EPHX2TRPV1ADORA2AADORA1 | |
| SCHEMBL18230379 | 0.80 | ADORA2A (0.71) | TRPV1ADORA2AADORA1SMN1; SMN2MAPT | |
| SCHEMBL18230521 | 0.80 | TRPV1 (0.59) | TRPV1ADORA2AADORA1SMN1; SMN2MAPT | |
| SCHEMBL18230442 | 0.79 | TRPV1 (0.52) | TRPV1ADORA2AADORA1TRPV4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |