Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548130 | 0.85 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16540066 | 0.84 | SLC6A3 (0.47) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16548207 | 0.83 | SLC6A3 (0.46) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16548087 | 0.83 | KMT2A (0.47) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16548090 | 0.82 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16548289 | 0.81 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16548208 | 0.81 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL16548215 | 0.80 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2ALDH1A1HPGD | |
| SCHEMBL18231367 | 0.77 | MAPT (0.48) | ALDH1A1HPGDKDM4EMAPTMEN1 | |
| SCHEMBL17950622 | 0.76 | CYP4F2 (0.44) | ALDH1A1HPGDKDM4ENPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |