SCHEMBL18236339

SCHEMBL18236339

CCCCCCCCCCCCN(CCN)CCNCCN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
DNM1 Q05193 9/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
EPHX1 P07099 1/20 0.39
CA12 O43570 2/20 0.39
CA6 P23280 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
RECQL P46063 1/20 0.39
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788518 0.96 CYP2C9 (0.50) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL18114372 0.96 CYP2C9 (0.50) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL3201509 0.96 CYP2C9 (0.50) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL11743886 0.94 ALDH1A1 (0.48) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL9322889 0.94 ALDH1A1 (0.48) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL8047263 0.94 ALDH1A1 (0.48) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL8002611 0.94 CYP2C9 (0.48) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL5406944 0.94 CYP2C9 (0.48) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL28364727 0.94 CYP2C9 (0.48) CYP2C9CYP2C19DNM1ALDH1A1TSHR
SCHEMBL11520236 0.92 ALDH1A1 (0.50) CYP2C9CYP2C19DNM1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160333288-A1 Cyclen Friction Modifiers for Boundary Lubrication UNITED STATES DEPARTMENT OF ENERGY 2016-11-17 US disclosed