Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615858 | 0.85 | PPARG (0.53) | PPARGPPARAPPARDMAPTMEN1 | |
| SCHEMBL2628180 | 0.85 | PPARG (0.53) | PPARGPPARAPPARDMAPTMEN1 | |
| SCHEMBL22312097 | 0.84 | NPSR1 (0.59) | MAPTMEN1KMT2ANPSR1TDP1 | |
| SCHEMBL17550410 | 0.80 | NPSR1 (0.54) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL6862461 | 0.80 | NPSR1 (0.54) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL12247705 | 0.80 | MAPT (0.61) | CTSKMAPTCTSLCTSBPOLB | |
| SCHEMBL699601 | 0.80 | MAPT (0.61) | CTSKMAPTCTSLCTSBPOLB | |
| SCHEMBL3818710 | 0.79 | CTSK (0.60) | CTSKMEN1KMT2AGAATDP1 | |
| SCHEMBL3498473 | 0.79 | CTSK (0.60) | CTSKMEN1KMT2AGAATDP1 | |
| SCHEMBL2101708 | 0.79 | PPARG (0.59) | CTSKPPARGPPARAPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016181312-A1 | POLYCYCLIC EPOXIDES AND COMPOSITIONS THEREOF WITH ANTI-CANCER ACTIVITIES | VERSITECH LIMITED (CN) | 2016-11-17 | — | — | WO | disclosed |