SCHEMBL1823752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1823919	0.93	SRC (0.52)	EGFRERBB2FLT4KDRFGFR1
	SCHEMBL1824546	0.86	RAF1 (0.47)	EGFRERBB2KDRFLT1ERBB4
	SCHEMBL1826544	0.85	EGFR (0.50)	EGFRERBB2AURKAERBB4BRAF
	SCHEMBL1822663	0.85	EGFR (0.47)	EGFRERBB2KDRRETERBB4
	SCHEMBL1826622	0.83	BRAF (0.56)	EGFRBRAF
	SCHEMBL4937677	0.82	SRC (0.57)	EGFRERBB2FLT4KDRFGFR1
	SCHEMBL4970476	0.82	EGFR (0.43)	EGFRERBB2FLT4KDRFGFR1
	SCHEMBL1824592	0.82	EGFR (0.43)	EGFRERBB2KDRERBB4BRAF
	SCHEMBL1824255	0.81	EGFR (0.50)	EGFRERBB2ERBB4MAP4K4MAPT
	SCHEMBL1825395	0.78	EGFR (0.52)	EGFRERBB2ERBB4MAP4K4BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.