Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.52 |
| ▸ | EGFR | P00533 | 16/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.52 |
| ▸ | KDR | P35968 | 5/20 | 0.52 |
| ▸ | KIT | P10721 | 3/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 3/20 | 0.52 |
| ▸ | RET | P07949 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | LTK | P29376 | 3/20 | 0.52 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.52 |
| ▸ | CIT | O14578 | 2/20 | 0.52 |
| ▸ | GAK | O14976 | 2/20 | 0.52 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.52 |
| ▸ | STK17B | O94768 | 2/20 | 0.52 |
| ▸ | STK10 | O94804 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | LYN | P07948 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823752 | 0.93 | EGFR (0.50) | SRCEGFRERBB2KDRKIT | |
| SCHEMBL4937677 | 0.90 | SRC (0.57) | SRCEGFRERBB2KDRKIT | |
| SCHEMBL4759186 | 0.86 | MAPT (0.57) | SRCEGFRERBB2KDRKIT | |
| SCHEMBL1824546 | 0.84 | RAF1 (0.47) | EGFRERBB2KDRERBB4BRAF | |
| SCHEMBL1826544 | 0.83 | EGFR (0.50) | EGFRERBB2ERBB4BRAFDYRK1A | |
| SCHEMBL1825737 | 0.83 | SRC (0.76) | SRCEGFRERBB2KDRKIT | |
| SCHEMBL1822663 | 0.83 | EGFR (0.47) | EGFRERBB2KDRERBB4RET | |
| SCHEMBL1826622 | 0.81 | BRAF (0.56) | EGFRBRAFDYRK1AALDH1A1 | |
| SCHEMBL1823364 | 0.81 | MAPT (0.64) | EGFRMAPK10IRAK4MAPTMAP4K4 | |
| SCHEMBL4970476 | 0.80 | EGFR (0.43) | EGFRERBB2KDRERBB4FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981876-B1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LTD (GB) | 2011-05-04 | — | — | EP | disclosed |
| US-20100158863-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2010-06-24 | — | — | US | disclosed |
| EP-1981876-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | Arrow Therapeutics Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007080401-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158863-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | SLC28A1, TPMT, ACE | SRC 3919/4885EGFR 4285/4885ERBB2 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.