Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852827 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL382392 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL2109252 | 0.74 | S1PR1 (0.35) | — | |
| SCHEMBL22048899 | 0.74 | GRM5 (0.51) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL20870315 | 0.73 | GRM5 (0.48) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL13340897 | 0.73 | ALDH1A1 (0.40) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL2111977 | 0.73 | S1PR1 (0.34) | — | |
| SCHEMBL21603210 | 0.73 | OGA (0.39) | GRM5 | |
| SCHEMBL23554439 | 0.72 | CYP3A4 (0.36) | ALDH1A1MAPT | |
| SCHEMBL21281640 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |