Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 8/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153187 | 0.79 | CDC7 (0.43) | CDC7PIM1PIM2GSK3BPARP1 | |
| SCHEMBL10081660 | 0.77 | GSK3B (0.36) | CDC7CDK9GSK3B | |
| SCHEMBL18237843 | 0.76 | P2RX7 (0.37) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL19131091 | 0.75 | CDC7 (0.47) | CDC7CDK9PIM1PIM2GSK3B | |
| SCHEMBL1805501 | 0.71 | HTR2A (0.38) | CDC7CDK9PIM1PIM2PARP1 | |
| SCHEMBL1805504 | 0.71 | HTR2A (0.38) | CDC7CDK9PIM1PIM2PARP1 | |
| SCHEMBL18237551 | 0.70 | HTR2A (0.33) | MEN1KMT2A | |
| SCHEMBL29361422 | 0.68 | GSK3B (0.47) | GSK3BTNKS2TDP2NSD2ABL1 | |
| SCHEMBL19117741 | 0.68 | GSK3B (0.47) | GSK3BTNKS2TDP2NSD2ABL1 | |
| SCHEMBL5155231 | 0.68 | TNKS2 (0.42) | GSK3BTNKS2TDP2NSD2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |