Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 18/20 | 0.60 |
| ▸ | TAB1 | Q15750 | 18/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948727 | 1.00 | MAP3K7 (0.60) | MAP3K7TAB1MTNR1AMTNR1BMEN1 | |
| SCHEMBL16949265 | 0.92 | MAP3K7 (0.59) | MAP3K7TAB1MTNR1AMTNR1BMEN1 | |
| SCHEMBL18238757 | 0.92 | MAP3K7 (0.59) | MAP3K7TAB1MTNR1AMTNR1BMEN1 | |
| SCHEMBL16945169 | 0.88 | MAP3K7 (0.54) | MAP3K7TAB1 | |
| SCHEMBL18238366 | 0.88 | MAP3K7 (0.54) | MAP3K7TAB1 | |
| SCHEMBL18238117 | 0.83 | MAP3K7 (0.53) | MAP3K7TAB1 | |
| SCHEMBL16945198 | 0.83 | MAP3K7 (0.53) | MAP3K7TAB1 | |
| SCHEMBL16932976 | 0.81 | MAP3K7 (0.58) | MAP3K7TAB1MTNR1AMTNR1B | |
| SCHEMBL16932974 | 0.81 | MAP3K7 (0.58) | MAP3K7TAB1MTNR1AMTNR1B | |
| SCHEMBL18238473 | 0.80 | MAP3K7 (0.41) | MAP3K7TAB1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499551-B2 | Substituted pyrrolo[2,3-b]pyridines for treating cancer or inflammatory diseases | CONFLUENCE LIFE SCIENCES, INC. (US) | 2016-11-22 | — | — | US | disclosed |