Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152670 | 0.76 | CRBN (0.39) | CRBNPDE3BPDE3A | |
| SCHEMBL18238541 | 0.71 | CRBN (0.34) | CRBNGSK3B | |
| SCHEMBL18238976 | 0.69 | KDM5B (0.31) | — | |
| SCHEMBL2510671 | 0.64 | KMT2A (0.44) | GSK3B | |
| SCHEMBL2502652 | 0.64 | L3MBTL1 (0.47) | GSK3B | |
| SCHEMBL18238526 | 0.63 | CRBN (0.33) | CRBNPDE3BPDE3A | |
| SCHEMBL18238957 | 0.63 | GSK3B (0.33) | GSK3B | |
| SCHEMBL18237570 | 0.63 | CRBN (0.33) | CRBNPDE3BPDE3A | |
| SCHEMBL18238972 | 0.63 | GSK3B (0.33) | GSK3B | |
| SCHEMBL13111251 | 0.62 | PDE3B (0.43) | CRBNPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |