Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.90 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.90 |
| ▸ | BLM | P54132 | 2/20 | 0.87 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.87 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.76 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430428 | 0.95 | CYP1A2 (1.00) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| Hydrochloric Acid SCHEMBL7194533 | 0.93 | BLM (1.00) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| Hydrochloric Acid SCHEMBL29651387 | 0.93 | BLM (1.00) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL13969525 | 0.92 | CYP3A4 (0.81) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| Hydrochloric Acid SCHEMBL10875595 | 0.91 | PMP22 (0.82) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL7266646 | 0.91 | CYP3A4 (0.79) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL3656443 | 0.91 | CYP3A4 (0.79) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL7266640 | 0.91 | CYP3A4 (0.79) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL11546332 | 0.91 | CYP3A4 (0.79) | CYP3A4CYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL6633115 | 0.91 | CYP3A4 (0.79) | CYP3A4CYP1A2CYP2D6BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127354-A1 | A PROCESS FOR THE PREPARATION OF VERAPAMIL HYDROCHLORIDE | Piramal Enterprises Limited (IN) | 2018-05-10 | — | — | US | disclosed |
| US-20180127354-A1 | A PROCESS FOR THE PREPARATION OF VERAPAMIL HYDROCHLORIDE | Piramal Enterprises Limited (IN) | 2018-05-10 | — | — | US | disclosed |
| WO-2016181292-A1 | A PROCESS FOR THE PREPARATION OF VERAPAMIL HYDROCHLORIDE | Piramal Enterprises Limited (IN) | 2016-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127354-A1 | A PROCESS FOR THE PREPARATION OF VERAPAMIL HYDROCHLORIDE | CACNA1I, CACNA1S, CACNA1C | CYP3A4 5/4885CYP1A2 110/4885CYP2D6 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.