Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TFEB | P19484 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TLR4 | O00206 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770107 | 1.00 | HTT (0.71) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL15066385 | 0.88 | GAA (0.60) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL15066386 | 0.88 | GAA (0.60) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL9185939 | 0.84 | HTT (0.76) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL9185934 | 0.84 | HTT (0.76) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL22904173 | 0.84 | HTT (0.51) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL13921688 | 0.84 | HTT (0.66) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL8698810 | 0.84 | HTT (0.56) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL9566179 | 0.84 | HTT (0.56) | HTTGAASMN1; SMN2LMNANFE2L2 | |
| SCHEMBL6714231 | 0.83 | HTT (1.00) | HTTGAASMN1; SMN2LMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114381156-B | Metal oxide dispersion composition, method for producing same, film composition containing same, optical film, and optical element | 凯斯科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114381156-A | Metal oxide dispersion composition, method for producing same, film composition containing same, optical film, and optical element | 凯斯科技股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114249956-A | Surface-modified metal oxide nanoparticle dispersion composition, method for producing same, film composition, and optical film | 凯斯科技股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| EP-3145935-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2017-03-29 | — | — | EP | disclosed |
| WO-2016188972-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | UNIVERSITEIT LEIDEN (NL) | 2016-12-01 | — | — | WO | disclosed |
| EP-3095787-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2016-11-23 | — | — | EP | disclosed |