Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | TFEB | P19484 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698810 | 1.00 | HTT (0.56) | HTTTRPA1TRPM8GAAKDM4E | |
| SCHEMBL6799880 | 0.85 | TRPA1 (0.52) | TRPA1TRPM8KDM4EHPGDMAPT | |
| SCHEMBL6799876 | 0.85 | TRPA1 (0.52) | TRPA1TRPM8KDM4EHPGDMAPT | |
| SCHEMBL18240122 | 0.84 | HTT (0.71) | HTTTRPA1TRPM8GAAKDM4E | |
| SCHEMBL7770107 | 0.84 | HTT (0.71) | HTTTRPA1TRPM8GAAKDM4E | |
| SCHEMBL6737719 | 0.80 | NFE2L2 (0.75) | TRPA1TRPM8KDM4EHPGDMAPT | |
| SCHEMBL1397474 | 0.80 | NFE2L2 (0.75) | TRPA1TRPM8KDM4EHPGDMAPT | |
| SCHEMBL10438847 | 0.78 | ALDH1A1 (0.58) | KDM4EHPGDMAPTHSD17B10NFE2L2 | |
| SCHEMBL69522 | 0.78 | ALDH1A1 (0.58) | KDM4EHPGDMAPTHSD17B10NFE2L2 | |
| SCHEMBL21710510 | 0.77 | KDM4E (0.83) | HTTTRPA1TRPM8KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |