Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240280 | 1.00 | CYP3A4 (0.41) | CYP3A4PAX8CYP11B1CYP11B2ACHE | |
| SCHEMBL16461662 | 0.88 | CYP3A4 (0.40) | CYP3A4PAX8CYP11B1CYP11B2ACHE | |
| SCHEMBL16461661 | 0.88 | CYP3A4 (0.40) | CYP3A4PAX8CYP11B1CYP11B2ACHE | |
| SCHEMBL16462011 | 0.84 | KMT2A (0.41) | CYP3A4PAX8CYP11B1CYP11B2ACHE | |
| SCHEMBL16462013 | 0.84 | KMT2A (0.41) | CYP3A4PAX8CYP11B1CYP11B2ACHE | |
| SCHEMBL2181651 | 0.83 | CYP11B1 (0.41) | CYP3A4PAX8CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL2181660 | 0.83 | CYP11B1 (0.41) | CYP3A4PAX8CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL16462241 | 0.82 | CYP3A4 (0.35) | CYP3A4PAX8ACHEBACE1APP | |
| SCHEMBL16462243 | 0.82 | CYP3A4 (0.35) | CYP3A4PAX8ACHEBACE1APP | |
| SCHEMBL29702273 | 0.74 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906529-B9 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA KS (CZ) | 2017-03-15 | — | — | EP | disclosed |
| EP-2906529-B1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA KS (CZ) | 2016-11-23 | — | — | EP | disclosed |