Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16462013 | 1.00 | KMT2A (0.41) | KMT2AMAPTMEN1LMNAPOLB | |
| SCHEMBL12931114 | 0.89 | MAPT (0.39) | KMT2AMAPTMEN1LMNAPOLB | |
| SCHEMBL16461661 | 0.88 | CYP3A4 (0.40) | MAPTHPGDPAX8CYP3A4CYP11B1 | |
| SCHEMBL16461662 | 0.88 | CYP3A4 (0.40) | MAPTHPGDPAX8CYP3A4CYP11B1 | |
| SCHEMBL1300340 | 0.85 | LMNA (0.41) | KMT2AMAPTMEN1LMNAPOLB | |
| SCHEMBL1300338 | 0.85 | LMNA (0.41) | KMT2AMAPTMEN1LMNAPOLB | |
| SCHEMBL18240280 | 0.84 | CYP3A4 (0.41) | KMT2AMAPTLMNAHPGDPAX8 | |
| SCHEMBL18240282 | 0.84 | CYP3A4 (0.41) | KMT2AMAPTLMNAHPGDPAX8 | |
| SCHEMBL931804 | 0.79 | CYP11B1 (0.59) | KMT2AMAPTMEN1LMNAPOLB | |
| SCHEMBL931806 | 0.79 | CYP11B1 (0.59) | KMT2AMAPTMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906529-B9 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA KS (CZ) | 2017-03-15 | — | — | EP | disclosed |
| EP-2906529-B1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA KS (CZ) | 2016-11-23 | — | — | EP | disclosed |
| EP-2906529-A1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | Zentiva K.S. (CZ) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014056464-A1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA, K.S. (CZ) | 2014-04-17 | — | — | WO | disclosed |