Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 19/20 | 0.70 |
| ▸ | OGFRL1 | Q5TC84 | 18/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 16/20 | 0.70 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240336 | 1.00 | OPRM1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL15004457 | 1.00 | OPRM1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL853102 | 0.98 | OPRM1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL21547905 | 0.98 | OPRM1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL852959 | 0.98 | OPRM1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL852958 | 0.98 | OPRM1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL16917792 | 0.91 | OGFRL1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL16368995 | 0.91 | OGFRL1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL15004422 | 0.90 | OGFRL1 (0.72) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL18645850 | 0.89 | OGFRL1 (0.63) | OPRM1OPRK1OGFRL1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654751-B1 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | PURDUE PHARMA LP (US) | 2016-11-23 | — | — | EP | disclosed |