Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240641 | 1.00 | ACP3 (0.51) | ACP3L3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL18240760 | 0.95 | FFAR1 (0.45) | ACP3L3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL18240761 | 0.95 | FFAR1 (0.45) | ACP3L3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL18240612 | 0.89 | ACHE (0.46) | ACP3NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL18240798 | 0.89 | HPGD (0.50) | NPC1MAPTRAB9ANPSR1ALDH1A1 | |
| SCHEMBL18240613 | 0.89 | ACHE (0.46) | ACP3NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL18240796 | 0.89 | HPGD (0.50) | NPC1MAPTRAB9ANPSR1ALDH1A1 | |
| SCHEMBL18240619 | 0.88 | FFAR1 (0.50) | NPSR1ALDH1A1CNR2KMT2ACNR1 | |
| SCHEMBL18240620 | 0.88 | FFAR1 (0.50) | NPSR1ALDH1A1CNR2KMT2ACNR1 | |
| SCHEMBL18240662 | 0.88 | GAA (0.41) | ACP3L3MBTL1NPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |