Styrene

Styrene

SCHEMBL1824349

C=Cc1ccccc1.Cc1ccc(O)cc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 2/20 0.58
ACHE P22303 2/20 0.54
TDP1 Q9NUW8 3/20 0.47
TP53 P04637 1/20 0.47
ESR1 P03372 3/20 0.44
CYP1B1 Q16678 2/20 0.42
MAPT P10636 4/20 0.41
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
POLB P06746 2/20 0.41
RAB9A P51151 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GLA P06280 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11761227 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTDP1ESR1CYP1B1
Styrene SCHEMBL28469781 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTDP1ESR1CYP1B1
Styrene SCHEMBL2361403 0.89 ALDH1A1 (0.74) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL9583045 0.87 ALDH1A1 (0.70) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL1974109 0.87 ALDH1A1 (0.70) ALDH1A1TSHRACHETDP1TP53
4-Vinylphenol SCHEMBL482342 0.87 ALDH1A1 (0.70) ALDH1A1TSHRTDP1ESR1CYP1B1
Styrene SCHEMBL8859296 0.84 ALDH1A1 (0.74) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL271801 0.84 ALDH1A1 (0.74) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL904376 0.84 ALDH1A1 (0.74) ALDH1A1TSHRTDP1TP53ESR1
Styrene SCHEMBL28670303 0.83 ALDH1A1 (0.64) ALDH1A1TSHRTDP1TP53ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150576-B1 STABILIZATION OF POLYMERS WITH STYRENATED-P-CRESOLS CHEMTURA CORP (US) 2011-05-04 EP claimed
CN-101688143-A Liquid styrene phenols composition and forming method thereof CHEMTURA CORP 2010-03-31 CN claimed
CN-101595172-A Method with vinylbenzene p-cresol stabilization of polymers CHEMTURA CORP (US) 2009-12-02 CN claimed
EP-0203879-B1 FUNCTIONALIZED MONOMERS FROM 1-(1-ISOCYANATO-1-METHYLETHYL)-3 OR 4-(1-METHYLETHENYL) BENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-05-02 EP claimed
EP-0064020-B1 SYNERGISTIC ANTIOXIDANT MIXTURES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-06-19 EP claimed
EP-0029797-B1 SYNERGISTIC ANTIOXIDANT MIXTURES, COMPOUNDS AND PROCESS FOR THEIR PRODUCTION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-10-19 EP claimed
JP-7070293-A None JP disclosed
CN-102267876-B Preparation method of styrenated hindered phenol or styrenated phenol antioxidant product UNIV CHANGZHOU 2014-06-18 CN disclosed
CN-101595172-B Method for stabilization of polymers with styrenated-p-cresols CHEMTURA CORP 2012-12-26 CN disclosed
CN-102267876-A Preparation method of styrenated hindered phenol or styrenated phenol antioxidant product UNIV CHANGZHOU 2011-12-07 CN disclosed
CN-102083900-A Storage-stable aqueous emulsions and liquid blends with low viscosity as stabilizers BASF SE 2011-06-01 CN disclosed
CN-101688143-A Liquid styrene phenols composition and forming method thereof CHEMTURA CORP 2010-03-31 CN disclosed
CN-101595172-A Method with vinylbenzene p-cresol stabilization of polymers CHEMTURA CORP (US) 2009-12-02 CN disclosed
CN-101595172-A Method with vinylbenzene p-cresol stabilization of polymers CHEMTURA CORP (US) 2009-12-02 CN disclosed
CN-101595172-A Method with vinylbenzene p-cresol stabilization of polymers CHEMTURA CORP (US) 2009-12-02 CN disclosed
JP-H0770293-A OXYALKYLENE ETHER, ANTISTATIC AGENT AND RESIN COMPOSITION SANYO CHEM IND LTD 1995-03-14 JP disclosed
CN-1092078-A Polymer finishing process UNION CARBIDE CHEM PLASTIC (US) 1994-09-14 CN disclosed