Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 12/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18943146 | 0.87 | PTGER4 (0.71) | PTGER4PTGER2 | |
| SCHEMBL22024730 | 0.84 | PTGER4 (0.72) | PTGER4PTGER2 | |
| SCHEMBL18943887 | 0.83 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL21658917 | 0.81 | PTGER4 (0.57) | PTGER4PTGER2 | |
| SCHEMBL21658906 | 0.81 | PTGER4 (0.57) | PTGER4PTGER2 | |
| SCHEMBL22025652 | 0.81 | PTGER4 (0.62) | PTGER4PTGER2 | |
| SCHEMBL20265939 | 0.78 | PTGER4 (0.69) | PTGER4PTGER2 | |
| SCHEMBL15549589 | 0.78 | PTGER4 (0.69) | PTGER4PTGER2 | |
| SCHEMBL21658898 | 0.78 | PTGER4 (0.47) | PTGER4PTGER2 | |
| SCHEMBL21658915 | 0.78 | PTGER4 (0.47) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160340306-A1 | DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS | CAYMAN CHEMICAL COMPANY, INCORPORATED | 2016-11-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340306-A1 | DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS | PTGER4, PTGER1, PTGER3 | PTGER4 1/4885PTGER2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.