Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.71 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22024730 | 0.96 | PTGER4 (0.72) | PTGER4PTGER2 | |
| SCHEMBL18943887 | 0.88 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL18244313 | 0.87 | PTGER4 (0.58) | PTGER4PTGER2 | |
| SCHEMBL16819586 | 0.86 | PTGER4 (0.84) | PTGER4PTGER2 | |
| SCHEMBL15586942 | 0.86 | PTGER4 (0.84) | PTGER4PTGER2 | |
| SCHEMBL19328518 | 0.86 | PTGER4 (0.84) | PTGER4PTGER2 | |
| SCHEMBL18943295 | 0.86 | PTGER4 (0.84) | PTGER4PTGER2 | |
| SCHEMBL16819584 | 0.86 | PTGER4 (0.84) | PTGER4PTGER2 | |
| SCHEMBL22025652 | 0.85 | PTGER4 (0.62) | PTGER4PTGER2 | |
| SCHEMBL20265939 | 0.84 | PTGER4 (0.69) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3175852-A1 | DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS | Cayman Chemical Company, Incorporated (US) | 2017-06-07 | — | — | EP | disclosed |