SCHEMBL1824441

SCHEMBL1824441

CC(=O)O[NH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Methyl Ester SCHEMBL8322448 0.67 ALDH1A1 (1.00)
SCHEMBL4318271 0.67
Ethaneperoxoic Acid SCHEMBL4954376 0.67 TSHR (0.55)
Acetic Acid Methyl Ester SCHEMBL3080739 0.67
Ethaneperoxoic Acid SCHEMBL562267 0.67 TSHR (0.55)
SCHEMBL1331774 0.67
SCHEMBL9866292 0.67
Acetic Acid Methyl Ester SCHEMBL3650 0.67
SCHEMBL523 0.67
SCHEMBL25442 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113350518-A Conjugated bridge linkers to cell binding molecules 杭州多禧生物科技有限公司 2021-09-07 CN claimed
US-7619003-B2 Process for producing optically active compound JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-11-17 US claimed
EP-1191929-A4 (Z)-STYRYL ACETOXYPHENYL SULFIDES AS CYCLOOXYGENASE INHIBITORS UNIV TEMPLE (US) 2005-02-16 EP claimed
EP-1303483-A4 NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORP (KR) 2004-11-03 EP claimed
US-6656968-B1 Selectively inhibit the cyclooxygenase activity of COX-2 over COX-1; addition polymers of compound TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2003-12-02 US claimed
US-20030153596-A1 Novel thiourea derivatives and the pharmaceutical compositions containing the same PACIFIC CORPORATION (KR) 2003-08-14 US claimed
EP-1303483-A1 NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORPORATION (KR) 2003-04-23 EP claimed
US-6469003-B1 COMPOUNDS HAVING CELL ADHESION INHIBITING ACTIVITY NIHON NOHYAKU CO., LTD. (JP) 2002-10-22 US claimed
EP-1191929-A2 (Z)-STYRYL ACETOXYPHENYL SULFIDES AS CYCLOOXYGENASE INHIBITORS Temple University of the Commonwealth System of Higher Education (US) 2002-04-03 EP claimed
WO-2002016318-A1 NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORPORATION (KR) 2002-02-28 WO claimed
WO-2000077169-A2 (Z)-STYRYL ACETOXYPHENYL SULFIDES AS CYCLOOXYGENASE INHIBITORS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2000-12-21 WO claimed
EP-0487768-B1 Pharmaceutical composition with improved dissolution property YOSHITOMI PHARMACEUTICAL (JP) 1995-01-25 EP claimed
US-4769384-A ANTIULCER AGENTS NIPPON SHINYAKU CO. LTD. (JP) 1988-09-06 US claimed
US-3948928-A ANTI-RESERPINE, CNS DEPRESSANT, HYPOTENSIVE, L-DOPA POTENTIATORS DAINIPPON PHARMACEUTICAL CO., LTD. (JA) 1976-04-06 US claimed
JP-60008851-A None JP disclosed
CN-113698335-A Specific conjugation of cell binding molecules 杭州多禧生物科技有限公司 2021-11-26 CN disclosed
CN-108811499-B Specific conjugation of cell binding molecules 杭州多禧生物科技有限公司 2021-09-24 CN disclosed
JP-S608851-A ELECTROSTATIC LATENT IMAGE DEVELOPING CARRIER RICOH CO LTD 1985-01-17 JP disclosed
EP-0102195-A2 Substituted aza bicycloalkyl derivatives with dopamine antagonist activity BEECHAM GROUP PLC (GB) 1984-03-07 EP disclosed
US-4377591-A CARBAPENICILLIN ANTIBIOTICS SANKYO COMPANY, LIMITED (JP) 1983-03-22 US disclosed