Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641099 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL1824796 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL383195 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7645599 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7642200 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL3683778 | 0.97 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL383448 | 0.97 | TSHR (0.48) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL3720954 | 0.95 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL43730 | 0.92 | — | — | |
| SCHEMBL10456179 | 0.87 | TSHR (0.43) | TSHRALDH1A1ALOX15KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855413-B1 | Ethylene copolymer rubber composition | JSR CORP (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5914372-A | VULCANIZABLE RUBBER CONSISTS OF A COPOLYMER OF ETHYLENE-ALPHA-OLEFIN-NON-CONJUGATED DIENE, ATLEAST ONE VULCANIZING AGENT, AND A PEROXY CROOSLINKING AGENT | JSR CORPORATION (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0855413-A1 | Ethylene copolymer rubber composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |