Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.63 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.62 |
| ▸ | EP300 | Q09472 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934770 | 0.94 | CETP (0.61) | CETPSOAT1EP300TSHRKDM4E | |
| SCHEMBL9549399 | 0.90 | CETP (0.65) | CETPSOAT1EP300TSHRHDAC3 | |
| SCHEMBL18248570 | 0.87 | CETP (0.62) | CETPSOAT1EP300TSHRHDAC3 | |
| SCHEMBL29952838 | 0.87 | HDAC3 (0.53) | SOAT1TSHRKDM4EALDH1A1GLA | |
| SCHEMBL9395051 | 0.86 | CETP (0.77) | CETPSOAT1EP300TSHRMAPK1 | |
| SCHEMBL5878480 | 0.86 | CETP (0.77) | CETPSOAT1EP300TSHRMAPK1 | |
| SCHEMBL10525639 | 0.86 | CETP (0.60) | CETPSOAT1EP300TSHRHDAC3 | |
| SCHEMBL7516912 | 0.86 | SOAT1 (0.63) | CETPSOAT1EP300TSHRHDAC3 | |
| SCHEMBL5295250 | 0.85 | CETP (0.53) | CETPSOAT1EP300TSHRKDM4E | |
| SCHEMBL29951577 | 0.84 | GAA (0.51) | KDM4EGAAHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297621-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | Dublin City University (IE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185025-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | DUBLIN CITY UNIVERSITY (IE) | 2016-11-24 | — | — | WO | disclosed |