Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952838 | 0.97 | HDAC3 (0.53) | GAAKCNQ2HDAC3HTTKDM4E | |
| SCHEMBL29951744 | 0.91 | CYP2C19 (0.56) | GAAKCNQ2HDAC3KDM4EKMT2A | |
| SCHEMBL6934770 | 0.86 | CETP (0.61) | GAAKCNQ2HDAC3HTTKDM4E | |
| SCHEMBL29955273 | 0.84 | KCNQ2 (0.56) | GAAKCNQ2HDAC3KMT2AMEN1 | |
| SCHEMBL18248481 | 0.84 | CETP (0.63) | GAAHDAC3KDM4EKMT2AHDAC1 | |
| SCHEMBL21665202 | 0.84 | HTT (0.60) | GAAHDAC3HTTKDM4EKMT2A | |
| SCHEMBL7822083 | 0.80 | HDAC3 (0.71) | GAAHDAC3KDM4EKMT2AMAPT | |
| SCHEMBL5144265 | 0.78 | HDAC3 (0.53) | KCNQ2HDAC3KMT2AMEN1MAPT | |
| SCHEMBL2555044 | 0.78 | KDM4E (0.50) | KCNQ2KDM4EKMT2A | |
| SCHEMBL2364756 | 0.78 | GAA (0.65) | GAAHDAC3HTTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |