Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643094 | 1.00 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248486 | 1.00 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Phosphoric Acid SCHEMBL29728497 | 0.94 | CHRM2 (0.49) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Phosphoric Acid SCHEMBL3688742 | 0.94 | CHRM2 (0.49) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL2984162 | 0.93 | CHRM3 (0.56) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL30448099 | 0.92 | CHRM3 (0.55) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248603 | 0.91 | SOAT1 (0.49) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248518 | 0.91 | SOAT1 (0.49) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248520 | 0.91 | SOAT1 (0.49) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248590 | 0.89 | KDM4E (0.52) | LMNAKDM4EMAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297621-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | Dublin City University (IE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185025-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | DUBLIN CITY UNIVERSITY (IE) | 2016-11-24 | — | — | WO | disclosed |