Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.49 |
| ▸ | SCN5A known ✓ | Q14524 | 3/20 | 0.48 |
| ▸ | SCN9A known ✓ | Q15858 | 3/20 | 0.48 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29728497 | 1.00 | CHRM2 (0.49) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL18248596 | 0.94 | CHRM3 (0.54) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL18248486 | 0.94 | CHRM3 (0.54) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL7643094 | 0.94 | CHRM3 (0.54) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL2984162 | 0.88 | CHRM3 (0.56) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| Hydrochloric Acid SCHEMBL30448099 | 0.86 | CHRM3 (0.55) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL18248603 | 0.86 | SOAT1 (0.49) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL18248518 | 0.86 | SOAT1 (0.49) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL18248520 | 0.86 | SOAT1 (0.49) | CHRM2CHRM3LMNACYP2D6CHRM1 | |
| SCHEMBL18248590 | 0.83 | KDM4E (0.52) | LMNAKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754792-B2 | Flame-retardant polyester artificial hair | KANEKA CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20080085957-A1 | Flame-Retardant Polyester Artificial Hair | KANEKA CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |