Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973582 | 0.77 | PARP1 (0.36) | MAPK1L3MBTL1KDM4ELMNAMEN1 | |
| SCHEMBL13835817 | 0.75 | IKBKB (0.37) | MKNK1MKNK2LMNAKMT2AALDH1A1 | |
| SCHEMBL3569772 | 0.69 | KDM4E (0.44) | KDM4EMEN1KMT2AIRAK4ALDH1A1 | |
| SCHEMBL3585656 | 0.69 | IRAK1 (0.43) | GLAKDM4EIRAK4ALDH1A1HPGD | |
| SCHEMBL29941277 | 0.66 | MKNK1 (0.48) | TSHRMAPK1MKNK1MKNK2GLA | |
| SCHEMBL6305012 | 0.66 | MKNK1 (0.48) | TSHRMAPK1MKNK1MKNK2GLA | |
| SCHEMBL3583270 | 0.66 | DGAT1 (0.36) | KDM4ELMNAHSD17B10ALDH1A1HPGD | |
| SCHEMBL16588903 | 0.65 | TLR8 (0.59) | TLR8GLAL3MBTL1KDM4ELMNA | |
| SCHEMBL5265677 | 0.65 | IRAK4 (0.44) | TLR8GLAKDM4EKMT2AIRAK4 | |
| SCHEMBL19329369 | 0.64 | PIM1 (0.49) | KDM4ELMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187544-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-11-24 | — | — | WO | disclosed |