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Sugi Predict / Compounds / SCHEMBL18249685

SCHEMBL18249685

SCHEMBL18249685

C=C(C)C(=O)OCCC[Si](C)(OC)OC.C=C(C)C(=O)OC[Si](OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.46
▸ THRB P10828 1/20 0.40
▸ POLB P06746 1/20 0.37
▸ APEX1 P27695 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3518915 0.91 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35128 0.91 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28098839 0.89 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL222686 0.86 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL978173 0.85 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28371093 0.85 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL4437900 0.85 TSHR (0.37) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5600819 0.84 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL977975 0.84 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28091162 0.84 TSHR (0.43) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3298092-A1 POLYMERS FOR DIRT-REPELLENT COATINGS Wacker Chemie AG (DE) 2018-03-28 — — EP disclosed
WO-2016184650-A1 POLYMERS FOR DIRT-REPELLENT COATINGS WACKER CHEMIE AG (DE) 2016-11-24 — — WO disclosed