SCHEMBL977975

SCHEMBL977975

C=C(C)C(=O)OCCCOCCC[Si](C)(OC)OC

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
THRB P10828 1/20 0.46
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509806 0.94 THRB (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35128 0.93 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28098839 0.92 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL222686 0.89 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL978173 0.88 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL18784855 0.88 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL976767 0.87 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3518915 0.87 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5600819 0.87 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223446 0.87 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101405315-B Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG 2011-04-13 CN disclosed
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
EP-1981924-B1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-03-31 EP disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
CN-101405315-A Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2009-04-08 CN disclosed
EP-1981924-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
WO-2007085620-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed