Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817391 | 0.86 | TSHR (0.57) | TSHRSMN1; SMN2CA1CA2GAA | |
| SCHEMBL19639292 | 0.80 | TSHR (0.44) | TSHRSMN1; SMN2CA1CA2GAA | |
| SCHEMBL3443844 | 0.75 | TDP1 (0.53) | CA1CA2GAASTK17BSTK17A | |
| SCHEMBL13107853 | 0.75 | TDP1 (0.53) | CA1CA2GAASTK17BSTK17A | |
| SCHEMBL12401895 | 0.75 | CA2 (0.53) | SMN1; SMN2CA1CA2NR1H4 | |
| SCHEMBL30981945 | 0.74 | SCD (0.41) | TSHRSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8381191 | 0.74 | ESRRG (0.48) | CA1CA2TRPV1 | |
| SCHEMBL12655254 | 0.74 | TSHR (0.57) | TSHRSMN1; SMN2HPGDLMNAHRH3 | |
| SCHEMBL991815 | 0.74 | TDP1 (0.54) | TSHRCA1CA2GAALMNA | |
| SCHEMBL18257735 | 0.73 | CA1 (0.47) | CA1CA2GAANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060395-A1 | CYCLIC UREAS USEFUL AS HIV INHIBITORS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |