Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537439 | 0.88 | PTPN1 (0.49) | PTPN1ITGB3ITGA2BSLC7A5ALPI | |
| SCHEMBL14247974 | 0.88 | PTPN1 (0.49) | PTPN1ITGB3ITGA2BSLC7A5ALPI | |
| SCHEMBL829349 | 0.88 | SLC7A5 (0.51) | PTPN1ITGB3ITGA2BSLC7A5ALPI | |
| Tyrosine SCHEMBL7795413 | 0.88 | SLC7A5 (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| Valine SCHEMBL17294090 | 0.84 | PTPN1 (0.43) | PTPN1ITGB3ITGA2BSLC7A5ALPI | |
| Glycine SCHEMBL2448454 | 0.84 | ITGB3 (0.47) | PTPN1ITGB3ITGA2BSLC7A5ALPI | |
| SCHEMBL11338509 | 0.81 | ANPEP (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| Isoleucine SCHEMBL29165062 | 0.80 | PTPN1 (0.42) | PTPN1ITGB3ITGA2BSLC7A5ALPI | |
| Tyrosine SCHEMBL3442321 | 0.79 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL3131432 | 0.79 | SLC7A5 (0.46) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298025-A1 | NEW AMINO ACID SEQUENCES WITH MICROBICIDAL ACTIVITY DERIVED FROM NAJA ATRA CARDIOTOXIN 1 (CTX-1) | Università degli Studi di Parma (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184855-A1 | NEW AMINO ACID SEQUENCES WITH MICROBICIDAL ACTIVITY DERIVED FROM NAJA ATRA CARDIOTOXIN 1 (CTX-1) | Università degli Studi di Parma (IT) | 2016-11-24 | — | — | WO | disclosed |