Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.59 |
| ▸ | RET | P07949 | 5/20 | 0.59 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692823 | 0.78 | ABL1 (0.72) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL18250098 | 0.77 | ABL1 (0.60) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL29496415 | 0.74 | ABL1 (1.00) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL18690708 | 0.74 | ABL1 (1.00) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL26148251 | 0.74 | MAPK1 (0.42) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL22664606 | 0.73 | MTOR (1.00) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL18250087 | 0.72 | DYRK3 (0.47) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL18258355 | 0.71 | SRC (0.62) | ABL1RETMTORFGFR2 | |
| SCHEMBL22664645 | 0.69 | MTOR (0.69) | ABL1RETMTORPIK3CDPIK3CA | |
| SCHEMBL22692825 | 0.69 | MTOR (1.00) | ABL1RETMTORPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298015-A1 | COMPOUNDS | The University Court of the University of Edinburgh (GB) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185160-A1 | COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2016-11-24 | — | — | WO | disclosed |