⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL2692899 | 1.00 | — | — | |
| Cyclopropane SCHEMBL11090628 | 1.00 | — | — | |
| Cyclohexane SCHEMBL28967114 | 0.84 | — | — | |
| SCHEMBL13468315 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL1542881 | 0.78 | ALDH1A1 (0.33) | — | |
| Cyclohexane SCHEMBL23142614 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL2761107 | 0.78 | ALDH1A1 (0.33) | — | |
| Cyclooctane SCHEMBL11038481 | 0.78 | ALDH1A1 (0.33) | — | |
| Cyclooctane SCHEMBL31262 | 0.78 | — | — | |
| Cyclohexane SCHEMBL2291099 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402319-B1 | DGAT Inhibitors | NOVARTIS AG (CH) | 2017-08-30 | — | — | EP | disclosed |
| US-20150065517-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2015-03-05 | — | — | US | disclosed |
| US-8912208-B2 | (4-{4-[5-(benzooxazol-2-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid useful for treating or preventing conditions or disorders associated with DGAT1 activity | NOVARTIS AG (CH) | 2014-12-16 | — | — | US | disclosed |
| US-8835451-B2 | Compounds | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | disclosed |
| EP-2418202-B1 | (4-[4-[5-(substituted amino)-pyridin-2-yl]phenyl]-cyclohexyl)-acetic acid derivatives as DGAT inhibitors | NOVARTIS AG (CH) | 2014-01-29 | — | — | EP | disclosed |
| US-20130018054-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2013-01-17 | — | — | US | disclosed |
| US-20130018074-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2013-01-17 | — | — | US | disclosed |
| EP-2418202-A1 | New compounds | Novartis AG (CH) | 2012-02-15 | — | — | EP | disclosed |
| EP-2404905-A1 | New compounds | Novartis AG (CH) | 2012-01-11 | — | — | EP | disclosed |
| EP-2402319-A1 | DGAT Inhibitors | Novartis AG (CH) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402317-A1 | DGAT inhibitor | Novartis AG (CH) | 2012-01-04 | — | — | EP | disclosed |
| EP-2301923-A1 | New compounds | Novartis AG (CH) | 2011-03-30 | — | — | EP | disclosed |
| US-20090247534-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2009-10-01 | — | — | US | disclosed |
| EP-2004607-A2 | NEW COMPOUNDS | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007126957-A2 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2007-11-08 | — | — | WO | disclosed |
| CN-1008911-B | Crosslinkable composition containing non-newtonian colloidal dispersion | LUBRIZOL CORP (US) | 1990-07-25 | — | — | CN | disclosed |
| CN-1008114-B | WATER-IN-OIL EMULSION | LUBRIZOL CORP (US) | 1990-05-23 | — | — | CN | disclosed |
| CN-86108192-A | The emulsion of Water in oil | — | 1987-09-09 | — | — | CN | disclosed |
| CN-86101020-A | The crosslinkable composite that contains the non newtonian colloidal dispersion system | — | 1986-10-08 | — | — | CN | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |