SCHEMBL18253252

SCHEMBL18253252

C=C(C)C(=O)Oc1ccc(C2CCC(OC(=O)C(=C)C)CC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
ATM Q13315 1/20 0.46
ELANE P08246 1/20 0.46
RAB9A P51151 2/20 0.35
MEN1 O00255 1/20 0.34
LSS P48449 2/20 0.33
ACACB O00763 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ESR2 Q92731 2/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
NPC1 O15118 1/20 0.32
HCRTR2 O43614 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14907532 1.00 KMT2A (0.46) KMT2AATMELANERAB9AMEN1
SCHEMBL17433314 0.96 KMT2A (0.43) KMT2AATMELANERAB9AMEN1
SCHEMBL22459764 0.88 KMT2A (0.39) KMT2AATMELANERAB9AMEN1
SCHEMBL20869340 0.86 KMT2A (0.37) KMT2AATMELANE
SCHEMBL27841780 0.85 KMT2A (0.48) KMT2AATMELANERAB9AMEN1
SCHEMBL17340245 0.85 KMT2A (0.39) KMT2AATMELANERAB9AESR2
SCHEMBL20869246 0.84 GPR174 (0.41) KMT2ARAB9AMEN1MRGPRX4SMN1; SMN2
SCHEMBL10660930 0.84 SLC18A3 (0.44) ELANERAB9ATDP1ALDH1A1NPC1
SCHEMBL1089780 0.84 KMT2A (0.49) KMT2AATMELANERAB9AMEN1
SCHEMBL20869189 0.83 PDE4B (0.41) SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877485-B1 LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-09-06 EP disclosed
US-20230029961-A1 LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-02-02 US disclosed
EP-3688118-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2021-05-19 EP disclosed
US-20200263091-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2020-08-20 US disclosed
WO-2019063585-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-04-04 WO disclosed
EP-2771735-B1 SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-01-24 EP disclosed
US-9568774-B1 Liquid crystal composition and method for manufacturing liquid crystal display apparatus including the same SAMSUNG DISPLAY CO., LTD (KR) 2017-02-14 US disclosed
US-9568774-B1 Liquid crystal composition and method for manufacturing liquid crystal display apparatus including the same SAMSUNG DISPLAY CO., LTD (KR) 2017-02-14 US disclosed
US-20160342029-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-24 US disclosed
US-20160342029-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-24 US disclosed
CN-102977896-B The manufacture method of liquid crystal display cells JSR CO., LTD. (JP) 2015-11-18 CN disclosed
CN-102311739-B The manufacture method of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CO., LTD. (JP) 2015-09-16 CN disclosed
CN-102004357-B Manufacture method of a liquid crystal display element, polymer composition and liquid crystal display element Jsr 2015-06-10 CN disclosed
CN-102977896-A Method for manufacturing liquid crystal display component JSR CORP 2013-03-20 CN disclosed
CN-102004357-A Manufacture method of a liquid crystal display element, polymer composition and liquid crystal display element Jsr 2011-04-06 CN disclosed